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Research priorities towards precision antibiotic therapy to improve patient care

| Gert Brouwer - webmaster | Publications

Research priorities towards precision antibiotic therapy to improve patient care

Z.P. Bulman, S.G. Wicha, E.I. Nielsen, J.R. Lenhard, R.L. Nation, U. Theuretzbacher, H. Derendorf, T. Tängdén, M. Zeitlinger, C.B. Landersdorfer, J.B. Bulitta, L.E. Friberg, J. Li, B. Tsuji
The Lancet Microbe, ahaed of print (2022).


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From Therapeutic Drug Monitoring to Model-Informed Precision Dosing for Antibiotics

| Gert Brouwer - webmaster | Publications

From Therapeutic Drug Monitoring to Model-Informed Precision Dosing for Antibiotics

SG Wicha, A.G. Märtson, E.I. Nielsen, B.C.P. Koch, L.E. Friberg, J.W. Alffenaar, I.K. Minichmayr
Clinical Pharmacology & Therapeutics, 109, 928-941 (2021).


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Concentration-dependent plasma protein binding: Expect the unexpected

| Gert Brouwer - webmaster | Publications

Concentration-dependent plasma protein binding: Expect the unexpected

RL Nation, U Theuretzbacher, BT Tsuji, on behalf of the International Society of Anti-Infective Pharmacology (ISAP)
European Journal of Pharmaceutical Sciences, 122, 341-346 (2018).


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International Consensus Guidelines for the Optimal Use of the Polymyxins.

| Gert Brouwer - webmaster | Publications

Framework for optimisation of the clinical use of colistin and polymyxin B: the Prato polymyxin consensus

| Gert Brouwer - webmaster | Publications

Framework for optimisation of the clinical use of colistin and polymyxin B: the Prato polymyxin consensus: RL Nation, J Li, O. Cars, W. Couet, MN Dudley, KS Kaye, JW Mouton, DL Paterson, VH Tam, U. Theuretzbacher, BT Tsuji, JD Turnidge.
The Lancet Infectious Diseases, Early Online Publication, 21 October 2014

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Individualised antibiotic dosing for patients who are critically ill: challenges and potential solutions

| Gert Brouwer - webmaster | Publications

Individualised antibiotic dosing for patients who are critically ill: challenges and potential solutions

Jason A Roberts, Mohd H Abdul-Aziz, Jeff rey Lipman, Johan W Mouton, Alexander A Vinks, Timothy W Felton, William W Hope, Andras Farkas, Michael N Neely, Jerome J Schentag, George Drusano, Otto R Frey, Ursula Theuretzbacher, Joseph L Kuti, on behalf of The International Society of Anti-Infective Pharmacology and the Pharmacokinetics and Pharmacodynamics Study Group of the European Society of Clinical Microbiology and Infectious Diseases

Lancet Infect Dis April 2014
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Importance of relating efficacy measures to unbound drug concentrations for anti-infective agents

| Gert Brouwer - webmaster | Publications

Importance of relating efficacy measures to unbound drug concentrations for anti-infective agents.

Gonzalez D, Schmidt S, Derendorf H.
Clin Microbiol Rev. 2013 Apr;26(2):274-88.

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New EMA guideline for antimicrobial development

| Gert Brouwer - webmaster | Publications

New EMA guideline for antimicrobial development.

Ambrose PG, Bhavnani SM, Dudley MN, Ellis-Grosse E, Rubino CM, Drusano GL.
Lancet Infect Dis. 2012 Apr;12(4):265-6.

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Saving Lives with Optimal Antimicrobial Chemotherapy

| Gert Brouwer - webmaster | Publications

Saving Lives with Optimal Antimicrobial Chemotherapy

Drusano GL, Lodise TP
Clin Infect Dis 2012 Oct 16

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Predicting bacterial fitness cost associated with drug resistance

| Gert Brouwer - webmaster | Publications

Predicting bacterial fitness cost associated with drug resistance.

Guo B, Abdelraouf K, Ledesma KR, Nikolaou M, Tam VH.
J Antimicrob Chemother. 2012 Apr;67(4):928-32.