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News November 2020

ISAP mourns the passing of Hartmut Derendorf

Dear colleagues and friends,

On November 23, 2020, our community lost a giant in our field and a remarkable human being: With heavy heart, we would like to share with you the devastating news that Hartmut Derendorf, Ph.D., our former President and longstanding ISAP member, passed away unexpectedly at the age of 67.

After studying Pharmacy and obtaining his Ph.D. in 1979 from the University of Münster, Germany, he joined the College of Pharmacy at the University of Florida, Gainesville, USA as a postdoctoral fellow in 1981, became a faculty member in 1983, and chaired the Department of Pharmaceutics for more than 25 years until his retirement in 2018. During that time, Hartmut become a leader in the field of modern pharmacokinetics and pharmacodynamics, long before such “scientific questions became mainstream questions”, as noted by his colleague and friend Ursula Theuretzbacher. Indeed, Hartmut mentored over 70 graduate students and 40 postdoctoral fellows and published over 500 publications. He earned numerous national and international awards for his research, e.g. the Volwiler Research Achievement Award from the American Association of Colleges of Pharmacy as well as the American College of Clinical Pharmacology (ACCP), Distinguished Investigator Award. Hartmut was also a former review panel member of the NASA Human Research Program, which investigated drug use during spaceflight, indicating the wide outreach of his research.

Our colleague Paul Tulkens remembered when Hartmut joined ISAP in 1995 at one of the founding meetings in Quebec City, Canada: “Hartmut presented a poster that we all very much appreciated because of its high scientific pharmacological content.  We all saw him as one of the future leaders in the discipline of antimicrobial PK/PD”, Paul said. He was right. Since then Hartmut was a longstanding, extremely active and passionate ISAP member. He served as President of ISAP from 2004-2006 and was a Council member for countless years until only a few weeks ago. He shaped the society tremendously. Roger Nation noted that Hartmut “had a deep love for ISAP and was a passionate advocate for its role in fostering the development of emerging antimicrobial chemotherapy scientists.” As an exceptional educator and caring mentor, he touched numerous lives, and inspired many young fellows to pursue a career in PK/PD and antimicrobial pharmacology, including myself. Hartmut did not only inspire, but took his role as a mentor very seriously and was “supportive like a father” of so many of us, as noted by Markus Zeitlinger.

Our thoughts are with his wife Kerry, his family and friends during this time of grieving the loss of this remarkable human being, who was not only an extremely gifted scientist, but also a humble and kind person with a heart of gold, positive attitude and sense of humor. He will be deeply missed by all of us.
Sebastian G. Wicha, President
on behalf of the International Society of Anti-Infective Pharmacology (ISAP)

News November 2020


On Tuesday, November 24 at 4PM CETJeremie Guedj from INSERM, Paris, France will deliver a webinar on the topic "Modeling SARS-Cov-2 viral dynamics to optimize therapy". The webinar is free for ISAP members and the dial-in information was sent to ISAP members via the newsletter. A recorded version of the webinar will be provided to ISAP members soon thereafter. Welcome!

News March 2020

COVID-19 pandemic

In light of the evolving situation around the world regarding COVID-19, we would like to update you all and provide a response to this global pandemic. After the cancellation of ECCMID, we will also will cancel our annual ISAP meeting.  We will reconvene with an ISAP meeting in the very near future.  

In order to provide a response to the rapidly changing COVID-19 environment:  

Now more than ever, although we are apart, we are together. We wish everyone to be safe, good health, and our very best wishes for those in the fight against COVID-19 around the globe and those conducting research in all fields in anti-infectives.

Sebastian and Brian  

News September 2020

ISAP Annual Meeting 2020

After we had to cancel our on-site meeting, which we inteded to hold in Paris in April, the ISAP 2020 meeting was held as a virtual meeting on Friday, September 18th, 12:00pm to 2:00pm (CEST) as an online meeting. The meeting report is online and can be found here. Thanks to all for joining!

News July 2019

ISAP mourns the loss of Johan Mouton 

Johan Mouton MD, Ph.D, passed away on July 9, 2019.  Johan was the President of ISAP from 2002 to 2004, one of the founding members of EPASG, and on the steering committee of EUCAST.  Johan received degrees in biology (Msc 1983), medicine (MD 1988) at the University of Utrecht, and completed his PhD in 1993 and training as a consultant medical microbiologist in 1994 at the Erasmus University in Rotterdam. Johan’s influence on the field of Pharmacokinetics and Pharmacodynamics was immeasurable. He spent over four decades studying the optimization of antimicrobial therapy and preventing resistance emergence through application of PK/PD principles.  Johan published a plethora of landmark papers, many of which standardized approaches in our field. An excellent example is his paper on standardization of PK/PD terminology for anti-infectives which has been cited over 400 times.  Johan strongly defended inclusion of PK/PD in the establishment of EUCAST breakpoints. His energy and drive was inspirational. There has been an outpouring of love and support for Johan from Scientists and Friends around the world. He will be dearly missed by our ISAP community.

Francoise Van Bambeke: “I am completely shocked by this very sad news. He strongly defended inclusion of PK/PD in the establishment of EUCAST breakpoints”

Zack Bulman: “This is extremely sad to hear. He was a true leader in our field.”

Juergen Bulitta: “Johan, will always remember you serving as the AAC editor for my first papers. Thank you for being a vivid and leading member of our community.”

Otto Cars: “We have lost a great  leader, inspirator, educator and a very good friend.”

William Couet: “Talentous and hard worker, happy to share his knowledge, but also curious and open to suggestions, Johan was a great leader and very pleasant partner. We'll miss him.”

Hartmut Derendorf: “Johan was so creative and full of energy, a tremendous inspiration and kind person”

Lena Friberg: “This is so sad, we have lost a  strong PKPD enthusiast with vast amount of knowledge. I will truly miss him as a person, and always remember his smile and inspirational energy”.

Jian Li: “Johan was really inspiring and we will miss him a lot. Johan was such a nice colleague in our community and made enormous contribution to PK/PD over decades Johan was not only a great scientist but also a wonderful friend.”

Roger Nation: “The news about Johan's passing is extremely sad. He made enormous contributions in the ID and antimicrobial chemotherapy arena and thereby to medicine more generally. His scientific and clinical acumen will be greatly missed, as will his insightful and inspirational role in so many organisations including EUCAST, EPASG and ISAP. With his research activities and publications, he was both prolific and, importantly, highly influential. As a result, his contributions to improving the use of antimicrobials will continue well into the future. Most important also, he was a wonderful and generous person. He was a great friend and fun to be around. He was a very special human being.”

Elisabet Nielsen: “Johan contributed enormously to the field of PKPD of antimicrobials, and we have lost a great leader, researcher, colleague and friend

Ursula Theuretzbacher: “He was a driving force in PK/PD and never ending supporter of this field. Whenever I had a specific question he always had an answer or at least had thought about it. We will miss his expertise and incredible experience and knowledge… I can't even think about any field where he was not instrumental.”

Paul Tulkens: “Johan was really inspiring and we will miss him a lot.”

Brian Tsuji: “Johan was an amazing leader in PK/PD for many decades who changed our field. He was always so inspiring with so much energy and passion.”

Thomas Walsh: “This is a tragic loss of a dear friend and colleague who contributed so very much to our understanding of antimicrobial agents and who mentored an entire generation of investigators in pharmacology.”

Sebastian Wicha: “Johan’s papers were the first ones I had read when I started my research career in PK/PD and I will also always remember the workshops he taught with so much passion at ECCMID”

Markus Zeitlinger: “At the moment we are too speechless to express how important Johan was to EPASG and the whole field of antimicrobial PK/PD and what a special person he was”