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Training

  • 11 - 12 April 2019

    Amsterdam, The Netherlands
    Optimised dosing of antibiotics – understanding PK/PD, clinical breakpoints and therapeutic drug monitoring
  • 3 - 4 June 2016

    Tübingen, Germany

    Individualized Medicine in Infectious Diseases: a Practical Approach

  • 13 - 16 April 2016

    Lyon, France

    Population Modeling and Dose Optimization with Pmetrics and BestDose: Antimicrobial Applications

  • 19 - 21 November 2015

    Warsaw, Poland
    Improving the Dosage of Old Antibiotics
  • 5 - 6 November 2015

    Ferney-Voltaire, France
    Moving Antimicrobial Stewardship Forward in Special Population Settings
  • 2 - 3 October 2014

    Annecy, France
    Postgraduate Education Course Infection Management in the Elderly: A Wide Room for Improvement
  • 6 - 8 October 2014

    Liverpool, United Kingdom
    Postgraduate Technical Workshop Advanced Antimicrobial Pharmacokinetic and Pharmacodynamic Modelling and Simulation
  • 16 - 18 September 2014

    Linz, Austria
    Postgraduate Technical Workshop 3rd Workshop on Antimicrobial Susceptibility Testing and Surveillance
  • 4 - 6 July 2014

    Nijmegen, The Netherlands

    Bringing PK and PD in Fungal Infections into the Clinic
    PEC-antifungal-PKPD-1wCourse Coordinators
    • Roger Brüggemann, Nijmegen, The Netherlands
    • Joseph Meletiadis, Athens, Greece
    • Ursula Theuretzbacher, Vienna, Austria
    • Andrew J. Ullmann, Würzburg, Germany

    Course Objectives
    • To learn PK/PD principles of antifungal therapy
    • To learn the pharmacokinetic differences among different patient populations
    • To understand resistance mechanisms of fungi and their impact on antifungal treatment
    • To learn how to use in vitro susceptibility data and to understand what breakpoints mean
    • To explore the utility of therapeutic drug monitoring, the principles of dose adjustment, and how to optimize the therapy
    • To understand the different clinical approaches of antifungal therapy and prophylaxis
    • To learn how to apply antifungal stewardship in your centre

    Faculty Members

    Roger Brüggemann, Nijmegen, The Netherlands              Joseph Meletiadis, Athens, Greece
    Werner Heinz, Würzburg, Germany Johan Mouton, Nijmegen, The Netherlands
    William Hope, Liverpool, United Kingdom Livio Pagano, Rome, Italy
    Christine Imbert, Poitiers, France Maurizio Sanguinetti, Rome, Italy
    Evelyne Jacqz-Agrain, Paris, France Ursula Theuretzbacher, Vienna, Austria
    Johan Maertens, Leuven, Belgium Andrew J. Ullmann, Würzburg, Germany
    Oscar Marchetti, Lausanne, Switzerland Paul Verweij, Nijmegen, The Netherlands
  • Oct 8-11, 2012

    Athens, Greece

    The ESCMID PK/PD Study Group organized a 4-day technical workshop in Athens, Greece, Oct 8-11, 2012
    A Statistical Approach to PK/PD Analysis in Practice
    EPASG-course-2012-1w
    Course Coordinators
    •     Eleftheria Mavridou, Nijmegen, NL
    •     Joseph Meletiadis, Athens, GR
    •     Johan W. Mouton, Nijmegen, NL
    Course Objectives
    •     Provide guidance on how to implement adequate statistical analysis to evaluate the pharmacokinetic and pharmacodynamic data
    •     Understand PK/PD indices, principles of CART analysis and how to apply these to establish
    clinical breakpoints
    •     Learn how to perform univariate and multivariate analysis, linear and nonlinear regression
    analysis, including the ins and outs of the Emax model
    •     To clarify the principles of pharmacokinetic parameters (peak and trough levels, volume of
    distribution, area under the concentration curve) and the factors that affect them
    •     Explain how to perform compartmental and non-compartmental pharmacokinetic analysis
    •     Understand how to measure and analyse drug combination effects and how to determine
    synergy and antagonism, including the Greco and Bliss models    
    •     Perform analysis with different software programs
    Faculty Members
    •     Saiden Abbas, Nijmegen, NL
    •     Roger Brüggemann, Nijmegen, NL
    •     William Hope, Manchester, UK
    •     Pavol Jancura, Nijmegen, NL
    •     Klaus Skovbo Jensen, Copenhagen, DK
    •     Eleftheria Mavridou, Nijmegen, NL
    •     Joseph Meletiadis, Athens, GR
    •     Johan W. Mouton, Nijmegen, NL
    •     Anouk E. Muller, Rotterdam, NL
    •     Ursula Theuretzbacher, Vienna, AT


Workshops

  • 2019 - ASM MICROBE WORKSHOP

    | Ursula Theuretzbacher | Activities - Workshops

    ASM microbe Workshop 2019

    Thursday, June 20 2019 at Mocscone Center, San Francisco, CA, USA, 12:30PM - 4:00PM

    Introduction to Pharmacokinetics/Pharmacodynamics: a Basic Primer

    Workshop Moderator
    Brian Tsuji; Univ. at Buffalo, Buffalo, NY
    Workshop Moderator
    Roger Nation; Monash Univ., Parkville, AL, Australia
    PK-PD Relationships of Antimicrobials: An introduction
    Brian Tsuji; Univ. at Buffalo, Buffalo, NY
    Concepts in Antimicrobial PK-PD: Linking to Humans
    Elizabeth Lakota; Inst. for Clinical Pharmacodynamics, Inc., Schenectady, NY
    Use of In-vitro Models to Elucidate the PK-PD Driver of Antimicrobial Activity
    Roger Nation; Monash Univ., Parkville, AL, Australia
    Animal Models and Their Use in Defining PK-PD Relationships
    Vincent Tam; Univ. of Houston, Houston, TX
  • 2018 - ISID WORKSHOP

    | Gert Brouwer - webmaster | Activities - Workshops

    ISID Workshop 2018

    18th Congress of the International Society for Infectious Diseases
    Saturday, March 3 2018
    at Sheraton Buenos Aires Hotel & Convention Center, Buenos Aires, Argentina, 5:00PM - 6:00PM

    Workshop session titled "Optimized Antibiotic Use"

    Individualized Antibiotics Use - an Introduction
    Ursula Theuretzbacher; CEFAIA, Vienna, Austria

    Bring your tablet – Individualized Antibiotic Dosing with Interactive Case Studies
    Sebastian Wicha; University of Hamburg, Hamburg, Germany
  • 2015 - ICAAC WORKSHOPS

    | Gert Brouwer - webmaster | Activities - Workshops

    ICAAC Workshops 2015

    Thursday, September 17 at San Diego Convention Center, CA, USA, 8:30AM - 4:30PM

     Workshop.55-01.Introduction to Pharmacokinetics/Pharmacodynamics 

    Workshop Convener
    Hartmut Derendorf, PhD - Professor
    Univ. of Florida Coll. of Pharmacy, Gainesville, FL.
    Workshop Convener
    Ursula Theuretzbacher, PhD - Principal
    Ctr. for Anti-Infective Agents, Vienna, Austria.
    Introduction to Pharmacokinetics
    Hartmut Derendorf, PhD - Professor
    Univ. of Florida Coll. of Pharmacy, Gainesville, FL.
    Introduction to Pharmacodynamics
    Ursula Theuretzbacher, PhD - Principal
    Ctr. for Anti-Infective Agents, Vienna, Austria.
    Linking Pharmacokinetics and Pharmacodynamics
    Johan Mouton, MD, PhD - Professor
    Radboud Univ. Nijmegen Med. Ctr., Nijmegen, Netherlands.
    Introduction to In vitro Infection Models
    Roger L. Nation, PhD - Professor
    Monash Univ., Melbourne, Australia.
    Introduction to In vivo Infection Models
    Vincent H. Tam, PharmD - Professor
    Univ. of Houston Coll. of Pharmacy, Houston, TX.
  • 2014 - ICAAC WORKSHOPS

    | Gert Brouwer - webmaster | Activities - Workshops

    ICAAC Workshops 2014

    Friday Sept. 5. 2014 at the Walter E. Washington Convention Center, Washington DC, USA, 8:30AM - 4:30PM

     Workshop.54-01.Introduction to Pharmacokinetics/Pharmacodynamics 

    Workshop Convener
    Hartmut Derendorf, PhD - Professor
    Univ. of Florida Coll. of Pharmacy, Gainesville, FL.
    Workshop Convener
    Ursula Theuretzbacher, PhD - Principal
    Ctr. for Anti-Infective Agents, Vienna, Austria.
    Introduction to Pharmacokinetics
    Hartmut Derendorf, PhD - Professor
    Univ. of Florida Coll. of Pharmacy, Gainesville, FL.
    Introduction to Pharmacodynamics
    Ursula Theuretzbacher, PhD - Principal
    Ctr. for Anti-Infective Agents, Vienna, Austria.
    Linking Pharmacokinetics and Pharmacodynamics
    Johan Mouton, MD, PhD - Professor
    Radboud Univ. Nijmegen Med. Ctr., Nijmegen, Netherlands.
    Introduction to In vitro Infection Models
    Roger L. Nation, PhD - Professor
    Monash Univ., Melbourne, Australia.
    Introduction to In vivo Infection Models
    William A. Craig, MD - Emeritus Professor
    Univ. of Wisconsin, Madison, WI.

    Workshop.54-03.Application of Pharmacokinetic/Pharmacodynamic Models

    Workshop Convener
    Sujata M. Bhavnani, PharmD, MS - Vice President
    ICPD, Latham, NY.
    Workshop Convener
    Alan Forrest, Pharm D - Research Professor and Senior Director of Pharmacometrics
    Univ. at Buffalo and Inst. of Clin. Pharmacodynamics, Buffalo, NY.
    Use of Population Pharmacokinetic Modeling in Therapeutic Drug Monitoring
    Alexander A. Vinks, PharmD, PhD - Professor
    Univ. of Cincinnati, Cincinnati, OH.
    Monte Carlo Simulation: Application to Dose Selection and Identification of Susceptibility Breakpoints
    Sujata M. Bhavnani, Pharm.D., M.S. - Vice President
    ICPD, Latham, NY.
    Modeling and Prediction of Anti-Infective Activity
    Alan Forrest, Pharm D - Research Professor and Senior Director of Pharmacometrics
    Univ. at Buffalo and Inst. of Clin. Pharmacodynamics, Buffalo, NY.
    Resistant Breakpoint Determination
    Alasdair MacGowan, MD - Professor
    North Bristol NHS Trust & Univ. of Bristol, Bristol, United Kingdom.
    Pharmacokinetics/Pharmacodynamics to Characterize and Overcome Resistance
    George Drusano, MD - Professor and Director
    Univ. of Florida, Orlando, FL.

    Workshop.54-02.Clinical Pharmacokinetics/Pharmacodynamics

    Workshop Convener
    Vincent H. Tam, PharmD - Professor
    Univ. of Houston Coll. of Pharmacy, Houston, TX.
    Workshop Convener
    Johan Mouton, MD, PhD - Professor
    Radboud Univ. Nijmegen Med. Ctr., Nijmegen, Netherlands.
    Clinical Application of Pharmacokinetics and Pharmacodynamics
    Vincent H. Tam, PharmD - Professor
    Univ. of Houston Coll. of Pharmacy, Houston, TX.
    Combination Therapy
    Johan Mouton, MD, PhD - Professor
    Radboud Univ. Nijmegen Med. Ctr., Nijmegen, Netherlands.
    Clinical Considerations of Obesity
    Manjunath Pai 
    Albany Coll. of Pharmacy and Hlth. Sci., Albany, NY
    Dosing in Special Patient Populations
    Markus Zeitlinger, MD - Associate Professor
    Med. Univ. Vienna, Vienna, Austria.
    Individualized Dosing and Therapeutic Drug Monitoring
    Thomas P. Lodise JR
    Albany Coll. of Pharmacy and Hlth. Sci., Albany, NY..

     Workshop.54-04.Pharmacokinetic/Pharmacodynamic Modeling of Anti-Infective Agents

    Workshop Convener
    David R. Andes, MD - Professor
    Univ. of Wisconsin, Madison, WI.
    Workshop Convener
    George Drusano, MD - Professor and Director
    Univ. of Florida, Gainesville, FL.
     In Vitro Dynamic Models for Antibiotic Pharmacokinetics-Pharmacodynamics
    Warren E. Rose
    Univ. of Wisconsin, Madison, WI
    Hollow Fiber System
    George Drusano, MD - Professor and Director
    Univ. of Florida, Gainesville, FL
    Animal Models for Pharmacokinetics/Pharmacodynamics
    David R. Andes, MD - Professor
    Univ. of Wisconsin-Madison, Madison, WI
    A Pharmacometric-Based Approach to Facilitate Critically Needed Development of New Antibiotics
    Sujata M. Bhavnani, PharmD, MS - Vice President
    ICPD, Latham, NY
    Mathematical Modeling: Software Choices
    Jurgen B. Bulitta
    Monash Univ. and SUNY-Buffalo, Parkville, Australia
  • 2013 - ICAAC WORKSHOPS

    | Ursula Theuretzbacher | Activities - Workshops

    ICAAC Workshops 2013

    Monday, September 9, 2013 at the Colorado Convention Center, Denver, USA, 8:30AM - 4:30PM

    Workshop.53-01.Introduction to Pharmacokinetics/Pharmacodynamics 

    Workshop Convener
    Hartmut Derendorf, PhD - Professor
    Univ. of Florida Coll. of Pharmacy, Gainesville, FL.
    Workshop Convener
    Ursula Theuretzbacher, PhD - Principal
    Ctr. for Anti-Infective Agents, Vienna, Austria.
    Introduction to Pharmacokinetics
    Hartmut Derendorf, PhD - Professor
    Univ. of Florida Coll. of Pharmacy, Gainesville, FL.
    Introduction to Pharmacodynamics
    Ursula Theuretzbacher, PhD - Principal
    Ctr. for Anti-Infective Agents, Vienna, Austria.
    Linking Pharmacokinetics and Pharmacodynamics
    Johan Mouton, MD, PhD - Professor
    Radboud Univ. Nijmegen Med. Ctr., Nijmegen, Netherlands.
    Introduction to In vitro Infection Models
    Roger L. Nation, PhD - Professor
    Monash Univ., Melbourne, Australia.
    Introduction to In vivo Infection Models
    William A. Craig, MD - Emeritus Professor
    Univ. of Wisconsin, Madison, WI.

    Workshop.53-03.Application of Pharmacokinetic/Pharmacodynamic Models

    Workshop Convener
    Sujata M. Bhavnani, PharmD, MS - Vice President
    ICPD, Latham, NY.
    Workshop Convener
    Alan Forrest, Pharm D - Research Professor and Senior Director of Pharmacometrics
    Univ. at Buffalo and Inst. of Clin. Pharmacodynamics, Buffalo, NY.
    Use of Population Pharmacokinetic Modeling in Therapeutic Drug Monitoring
    Alexander A. Vinks, PharmD, PhD - Professor
    Univ. of Cincinnati, Cincinnati, OH.
    Predicting Pharmacokinetic Variability Using Stochastic Simulation
    Sujata M. Bhavnani, Pharm.D., M.S. - Vice President
    ICPD, Latham, NY.
    Modeling and Prediction of Anti-Infective Activity
    Alan Forrest, Pharm D - Research Professor and Senior Director of Pharmacometrics
    Univ. at Buffalo and Inst. of Clin. Pharmacodynamics, Buffalo, NY.
    Resistant Breakpoint Determination
    Alasdair MacGowan, MD - Professor
    North Bristol NHS Trust & Univ. of Bristol, Bristol, United Kingdom.
    Pharmacokinetics/Pharmacodynamics to Characterize and Overcome Resistance
    George Drusano, MD - Professor and Director
    Univ. of Florida, Orlando, FL.

    Workshop.53-02.Clinical Pharmacokinetics/Pharmacodynamics

    Workshop Convener
    Vincent H. Tam, PharmD - Professor
    Univ. of Houston Coll. of Pharmacy, Houston, TX.
    Workshop Convener
    Johan Mouton, MD, PhD - Professor
    Radboud Univ. Nijmegen Med. Ctr., Nijmegen, Netherlands.
    Clinical Application of Pharmacokinetics and Pharmacodynamics
    Vincent H. Tam, PharmD - Professor
    Univ. of Houston Coll. of Pharmacy, Houston, TX.
    Combination Therapy
    Johan Mouton, MD, PhD - Professor
    Radboud Univ. Nijmegen Med. Ctr., Nijmegen, Netherlands.
    Dosing in Special Patient Populations
    Markus Zeitlinger, MD - Associate Professor
    Med. Univ. Vienna, Vienna, Austria.
    Individualized Dosing and Therapeutic Drug Monitoring
    Jason A. Roberts, PharmD, PhD - Consultant Clinical Pharmacist
    Royal Brisbane and Women’s Hosp. & Univ. of Queensland, Brisbane, Australia.
    Clinical Study Design Based Upon Pharmacokinetics/Pharmacodynamics
    Sujata M. Bhavnani, Pharm.D., M.S. - Vice President
    ICPD, Latham, NY.

    Workshop.53-04.Pharmacokinetics/Pharmacodynamics in Non-Bacterial Infections

    Workshop Convener
    David R. Andes, MD - Professor
    Univ. of Wisconsin, Madison, WI.
    Workshop Convener
    George Drusano, MD - Professor and Director
    Univ. of Florida, Orlando, FL.
    Anti-Fungal Pharmacokinetics/Pharmacodynamics
    David R. Andes, MD - Professor
    Univ. of Wisconsin, Madison, WI.
    Anti-Tuberculosis Pharmacokinetics/Pharmacodynamics
    Tawanda Gumbo, MD - Associate Professor of Medicine
    UT Southwestern Med. Ctr., Dallas, TX.
    Anti-Viral Pharmacokinetics/Pharmacodynamics
    George Drusano, MD - Professor and Director
    Univ. of Florida, Orlando, FL.
    Anti-Malaria Pharmacokinetics/Pharmacodynamics
    Nicholas J. White, MD, FRS - Professor of Tropical Medicine
    Mahidol Univ. and Oxford Univ., Bangkok, Thailand.

     

     

  • 2012 - ICAAC WORKSHOPS - San Francisco

    | Ursula Theuretzbacher | Activities - Workshops

    ICAAC Workshops 2012
    Saturday, September 8, 2012, San Francisco, USA

    Moscone Center (Esplanade Ballrooms)

    Workshop 01 (Derendorf/Mouton) Basics of Pharmacokinetics and Pharmacodynamics of Anti-Infective Agents

    8:30 - 8:40 am

    Conveners

    Introduction

    8:40 – 9:10 am

    H. Derendorf

    Introduction to PK/PD + discussion

    9:10 – 9:40 am

    J. Mouton

    PK/PD indices + discussion

    9:40 - 10:10 am

    U. Theuretzbacher

    Protein Binding/Tissue Distribution + discussion

    10:10 - 10:30 am

    Break

    10:30 – 11:00 am

    R. Nation

    In vitro models + discussion

    11:00 - 11:30 am

    W. Craig

    Animal models + discussion

    11:30 – 12:00 am

    A. MacGowan

    In vitro resistance + discussion

     

    Workshop 02 (Mouton/Theuretzbacher) Clinical Relevance of Pharmacokinetics and Pharmacodynamics of Anti-Infective Agents

    1:00 – 1:10 pm

    Conveners

    Introduction

    1:10 – 1:40 pm

    J. Mouton

    Clinical applications of PK/PD + discussion

    1:40 – 2:10 pm

    M. Zeitlinger

    Drug exposure at infection site + discussion

    2:10 – 2:40 pm

    S. Bhavnani

    Clinical study design based on PK/PD + discussion

    2:40 – 3:00 pm

    Break

    3:00 – 3:30 pm

    U. Theuretzbacher

    Clinical resistance  + discussion

    3:30 – 4:00 pm

    D. Andes

    PK/PD of antifungals + discussion

    4:00 – 4:30 pm

    P. Tulkens

    Dosing in specific situations + discussion

     

    Workshop 51-03 (Tam/Vinks) Introduction to PK/PD Modeling of Anti-Infective Agents

    8:30 - 8:40 am

    Conveners

    Introduction

    8:40 – 9:10 am

    A. MacGowan

    Approach to clinical breakpoints + discussion

    9:10 – 9:40 am

    V. Tam

    PK/PD modeling of resistance + discussion

    9:40 - 10:10 am

    J. Crandon

    PK/PD approaches in drug development + discussion

    10:10 - 10:30 am

    Break

    10:30 – 11:00 am

    A. Vinks

    Population PK/PD modeling of anti-infective agents + discussion

    11:00 - 11:30 am

    A. Forrest

    Modeling of anti-infective activity + discussion

    11:30 – 12:00 am

    S. Bhavnani

    Monte Carlo Simulations + discussion

     

    Workshop 51-04 (Drusano/Derendorf) Advanced PK/PD Modeling of Anti-Infective Agents with Practical Examples

    1:00 – 1:10 pm

    Conveners

    Introduction

    1:10 – 1:55 pm

    H. Derendorf

    PK/PD based on kill curves + discussion

    1:55 – 2:40 pm

    A. Forrest

    Modeling of anti-infective activity + discussion

    2:40 – 3:00 pm

    Break

    3:00 – 3:45 pm

    G. Drusano

    PK/PD in drug development + discussion

    3:45 – 4:30 pm

    J. Bulitta

    PK/PD models of resistance + discussion