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ISAP Newsletter November 2022

ISAP Newsletter November 2022
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         November 2022


Dear colleagues,
Please take note of the following events that are taking place. Furthermore, the call for mentees for the next ISAP Mentoring program 2023 is open now!
Meeting at the International Congress of Antimicrobial Chemotherapy (ICC)
In conjunction to the International Congress of Antimicrobial Chemotherapy (ICC) that will be held in Perth, Australia at the end of this November, we are having a hybrid meeting on the Wed, 30th November 2022 at 8:30 – 10:00 am AWST (6:30 – 8:00 pm CST; 12:30 – 2:00 am UTC, for those joining us virtually). This meeting will discuss upcoming plans/activities for the working group and we would like to hear from you.
If you are going to attend the ICC, we will follow up with another email on the location of the meeting when we are closer to the date.

Please use the following Zoom link to join us virtually if you are unable to attend the onsite meeting.
Meeting ID: 872 4472 9441
Passcode: 047868
Please save the date and we are looking forward to meeting you in Perth soon!
Best wishes,
Jian Li on behalf of the ISAC Anti-Infective Pharmacology Working Group
Webinar by EPASG on the 16th Dec – Save the date!
There will be a webinar organized by EPASG on the 16th Dec from 12:00 – 13:00 CET. Prof Birgit Koch will speak about: To TDM or not to TDM? Successes and limitations of model-informed precision dosing of antibiotics in special populations. More details will follow when we are closer to the date. Please save the date and we are looking forward to seeing you.
Call for new Mentees for the ISAP Mentoring Program 2023 is open now!

We are pleased to announce that the ISAP Mentoring program is going into the second round. Don’t miss the chance to join and discuss your personal, scientific and career questions with international senior scientists. The Mentoring program will start in January/February 2023, will last 1 year. Moreover, you will receive a certificate of the ISAP Mentoring program. The program is coordinated by Alina Nussbaumer-Pröll (Vienna, Austria). Below you find the profiles of our ISAP mentors. All Young Investigators are welcome to join! To join the program please contact Alina ( and indicate which team you wish to join. Please provide two choices so balanced groups can be created. Deadline for application is the end of December.

Mentoring profiles
Sebastian Wicha and Alina Nussbaumer-Pröll
Sebastian Wicha is head of the Department of Clinical Pharmacy at the Institute of Pharmacy of the University of Hamburg, Germany. His research focus is dedicated to contribute to the rational use of medicines (mainly anti-infectives) using in vitro, bioanalytical and pharmacometric approaches.
Alina Nussbaumer-Pröll is Post-Doc at the Department of Clinical Pharmacology, Medical University of Vienna, Austria. Her research focus lies on antibiotic susceptibility testing (MIC, TKC) in combination with vitro PK/PD Hollow Fiber Infection Models (HFIM). Moreover, she has expertise in Phase I Clinical Trials, which are conducted frequently at her home department.
Together they want to offer a welcoming atmosphere in the mentoring group to discuss topics related to science, career, and networking.

Jian Li and Zack Bulman
Jian Li is a Professor and Head of the Laboratory of Antimicrobial Systems Pharmacology at Monash University in Australia. He has an internationally recognised track record in antimicrobial pharmacology, particularly for the polymyxins. His research interests include systems pharmacology, drug development, and pre-clinical pharmacokinetics/pharmacodynamics (PK/PD). Zack Bulman is an Assistant Professor at the University of Illinois at Chicago College of Pharmacy. His research aims to develop new treatment strategies for resistant Gram-negative infections using a combination of preclinical PK/PD models and molecular approaches. Their international mentorship team hopes to provide guidance for career development and networking.

Lena Friberg and Iris Minichmayr
Lena Friberg is a Professor in Pharmacometrics at Uppsala University, Sweden. Her research focuses on the development of population pharmacokinetic and pharmacodynamic (PKPD) models for desired effects and adverse events to aid dose optimization and model-based translation within infectious diseases and other therapeutic areas. The developed frameworks, integrating in vitro, in vivo and clinical data, aim to make transitions between the different phases of drug development more efficient.
Iris Minichmayr is a pharmacist by training and a researcher in the Uppsala Pharmacometrics Research group. Her research interests include, but are not limited to, PKPD modelling of antimicrobials in special patient populations, in vitro-in vivo translational predictions of antibiotic effects, as well as model-informed precision dosing and therapeutic drug management.
Both have an international scientific background, are active in diverse scientific communities and editorial boards of scientific journals (particularly focusing on pharmacometrics, clinical pharmacology, translation and/or infectious diseases), and are happy to give advice and constructive feedback on issues of research, career development, networking opportunities, publishing in scientific journals or other topics of interest.

Charlotte Kloft, Robin Michelet and Linda Aulin
Charlotte Kloft is head of the Department of Clinical Pharmacy and Biochemistry at Freie Universitaet Berlin (FUB), Germany. Her expertise covers pharmacometric data analysis of preclinical and clinical data in various therapeutic areas and special patient populations, as well as in vitro systems to investigate pharmacokinetics/pharmacodynamics of anti-infectives. She constitutes a mentoring group with Robin Michelet (FUB) and Linda Aulin (FUB), looking forward to scientific exchange, sharing knowledge and experience.

Roger Nation and Cornelia Landersdorfer
Cornelia Landersdorfer leads a research group on antibiotic pharmacokinetics/pharmacodynamics (PK/PD) and dosage regimen optimisation at Monash University. She has expertise in dynamic in vitro infection models, mechanism-based modelling and population PK modelling. The research focus of her laboratory is to integrate experimental microbiological studies with mathematical modelling to optimise dosing of current and new antibiotics. Roger Nation has recently retired as Professor of Drug Disposition and Dynamics at Monash University where he continues with the same professorial title as an honorary appointment. He has expertise in both non-clinical and clinical pharmacological studies. Over the last 25 years his focus has been on the application of PK/PD in the dose optimization of antibiotics, especially the polymyxins. They would like to offer to mentees informal discussions on topics related to translation, publication strategy and career planning.
Best regards,
ISAP Council

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