hdr isap 2019

Annual meeting 2022

Optimised dosing of antibiotics – understanding PK/PD, clinical breakpoints and therapeutic drug monitoring

A 2 day course on PK/PD of anti-infectives was held as a pre-meeting to ECCMID at April 20 -21 2022 in Lisbon, Portugal. The course was organized in collaboration with EPASG and very well attended.

Foto 210422 09 13 43

The program of the course can be found here

ISAP General and Scientific Meeting

Immediately following the educational course, we held our general meeting and reflected on our scientific and educational acitivities of the past two years, followed by the traditional ISAP Young investigator session, chaired by Dr. Alina Nussbaumer-Pröll (Vienna) and Dr. Vincent Aranzana-Climent (Poitiers). 

The following Young Investigators presented their work:

First name

Last Name

Title

Aneeq

Farooq

Interaction screening of ceftazidime-avibactam and tigecycline against six clinical and nine isogenic E. coli and K. pneumoniae strains expressing carbapenemases

Wisse

Van Os

Impact of individual ascitic fluids on bacterial growth and ceftriaxone effect in an in vitro model of spontaneous bacterial peritonitis

Nicole

Zimmermann

Integrated in vitro approach to understand the exposure-effect relationship of fosfomycin against Escherichia coli

Amaury

O'Jeanson

A model-based analysis of pharmacokinetic-pharmacodynamic (PK/PD) indices of avibactam against β-lactamase-producing Gram-negative bacteria

Jinxin

Zhao

PhageGE: An Interactive Web-based R Shiny Application for Bacteriophage Pharmacology

Sue

Nang

Elucidating the pharmacokinetics/ pharmacodynamics of bacteriophage therapy against Pseudomonas aeruginosa using a mouse bacteraemia model

Romain

Aubry

Semi-mechanistic PKPD modelling of ceftazidime/avibactam and colistin combination against five multidrug resistant Klebsiella pneumoniae isolates

Mathilde

Lacroix

In vitro PK/PD modelling of polymyxin B against resistant strain of A. baumannii in presence of mucin

Matthias

Gijsen

Model-based TDM of vancomycin: a retrospective comparison with routine TDM-based dosing

Gert-Jan

Wijnant

Pharmacokinetics and PK/PD of temocillin in non-ICU urinary tract infection patients with various stages of renal insufficiency

Tim

Ewoldt

Large variability of unbound active fraction of ceftriaxone in contrast to ciprofloxacin in plasma of critically ill patients

Maria

Sanz Codina

Relationship between pharmacokinetic/pharmacodynamic target attainment and microbiological outcome in critically ill COVID-19 patients with documented Gram-negative superinfections treated with meropenem continuous infusion

Foto 220422 18 08 25

ISAP Young Investigators

 

The audience voted for the best Young Investigator presentations: 

Wisse Van Os (Medical University of Vienna, Austria)

Gert-Jan Wijnant (UCLouvain, Belgium)

 Foto 220422 19 22 34

The winner of the Young Investigator session Wisse van Os (3rd from left) and runner-up Gert-Jan Wijnant (3rd from right) together with the Young Investigator session chairs Alina Nussbaumer-Pröll and Vincent Aranzana Climent (right) and Sebastian Wicha (President of ISAP) and Markus Zeitlinger (Chair of EPASG) (left).

Foto 220422 19 24 24

All attendees of the ISAP meeting.