hdr isap 2019

The International Society of Anti-Infective Pharmacology is an interdisciplinary scientific society for the study of pharmacodynamics and pharmacokinetics and for the improvement of dosing of anti-infectives. The Society efforts are focused on expanding basic and applied knowledge in this area of chemotherapeutics through the organization of symposia, discussion workshops , and educational workshops with international participation, in connection with major scientific meetings dealing with the chemotherapy of infectious diseases (ASM microbe, ICC, ECCMID ...), and other scientific societies with common interests, and Regulatory Authorities (FDA, EMA).


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International Journal of Antimicrobial Agents: Call for Associate Editors and Editors-in-Training

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The International Journal of Antimicrobial Agents (IJAA) is an official journal of the International Society of Antimicrobial Chemotherapy (ISAC). IJAA focuses on the physical, pharmacological and clinical properties of antimicrobial agents (antivirals, antibacterials, antifungals, antiparasitics, etc), as well as signalling new trends and developments in the field through highly authoritative review articles on antimicrobial agents.

The Journal is now recruiting Associate Editors (4-year term) and Editors-in-Training (2-year term). Such positions offer great opportunities to expand your network with fellow editorial board members globally and to learn the publication dos and don’ts. Of note, IJAA endeavours to foster a culture that values equity, diversity (e.g., gender balance and culture background), and inclusivity, and our publishing team will provide all necessary training and ongoing support to successful candidates.

Associate Editors

Roles of an Associate Editor include:

  • Assessing the suitability of manuscripts for peer review.
  • Identifying suitable reviewers who meet the journal’s selection requirements.
  • Making publication decisions based on your own and the peer reviewers’ assessments.
  • Soliciting manuscript submissions.

If you are an expert in the field of antibacterials, antivirals, antifungals, antiparasitics, fundamental antimicrobial pharmacology, surveillance on antimicrobial resistance and One Health, we welcome you to express your interest by emailing the Editor-in-Chief Professor Jian Li (This email address is being protected from spambots. You need JavaScript enabled to view it.) with your latest CV by 31 May 2023. Associate Editor candidates with prior editorial experience are preferred but this is not an essential requirement.

Editors-in-Training

IJAA aspires to recognise and reward outstanding young-generation scientists in the field. For young investigators who are within 5 years post PhD, here is your chance to join the Journal’s Editorial Team as an Editor-in-Training. This role offers a unique opportunity to be introduced into the operations of the journal and gain valuable editorial experience for future career development. If you want to be considered for an Editor-in-Training position, we encourage you to send your CV to Professor Jian Li by 31 May 2023.

We are looking forward to welcoming you to the Editorial Team of the International Journal of Antimicrobial Agents!

 

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Openings  

Job openings

PhD student in microbiology and mathematical modelling
Organization/company:
Location: INSERM U1070, Poitiers
Country: France
Website: https://phar.labo.univ-poitiers.fr/
Mandatory degree: Master 2
Application deadline: 11th June 2023
Starting date: 01/09/2023
Type of contract:  Full-time 3 years
Funding: ANR/JPIAMR programs
Net salary: approximately 1650 €/month

Offer Description :
The candidate will work on two international collaborative projects DeCa-P (1) and STARS-TAP (2). These international projects will involve extensive collaboration with the microbiology team of Christian Lesterlin and Sarah Bigot in Lyon, France (3).

In DeCa-P, we aim to better understand emergence of multi-drug resistant bacteria through study of plasmidic transfer. More precisely we aim to find genetic and environmental factors influencing the plasmidic transfer abilities and rate. To do so, we will focus on the pOXA-48a
conjugative plasmid that encodes an OXA-family carbapenemase responsible for carbapenem resistance among Enterobacteriaceae.

In STARS-TAP, plasmids rather than being foes are turned into friends. Indeed, Targeted-Antibacterial-Plasmids (4) (TAPs) are plasmids that use DNA conjugation to deliver CRISPR/Cas systems to specifically target and kill specific bacterial strains based on their genome. If successful, the use of TAPs would enable preventive removal of strains harboring drug-resistance strains from microbiomes.

In this project the candidate will have two main tasks: 1) perform in vitro microbiology experiments (MIC, time-kill curves) where the effect of antibiotics on plasmidic transfer ability and rate (DeCa-P) and evaluate the combined efficacy of TAPs with antibiotics (STARS-TAP); 2)
develop mathematical models to quantify plasmidic transfer rates, genetic and environmental impact on these rates, TAPs + antibiotic efficacy. The models will be based on in vitro data generated in both projects by the candidate and the project partners.

The successful candidate will be part of our research unit affiliated to the University of Poitiers and INSERM. We are a transversal group created in 2012 with the aim to optimize antibiotic usage through collaboration between microbiologists, pharmacologists, pharmacometricians, drug formulation researchers, cellular biologists, chemical analysts and clinicians.

We are developing innovative pharmacokinetic-pharmacodynamic (PKPD) modelling approaches to select the best dosing regimen of antibiotics administered alone or in combination as well as the best route of administration and best formulation. We conduct translational research, from cell culture to patients, by integrating microbiology, analytical chemistry, drug formulation, and in vivo preclinical experiments.

(1) https://anr.fr/en/funded-projects-and-impact/funded-projects/project/funded/project/b2d9d3668f92a3b9fbbf7866072501ef-19df2359fe/?tx_anrprojects_funded%5Bcontroller%5D=Funded&cHash=840f705f08c823248d580523e9f56b98
(2) https://www.jpiamr.eu/old-projects/stars-tap/
(3) http://tacc.ibcp.fr/index.html
(4) https://academic.oup.com/nar/article/49/6/3584/6154464

Qualifications :
- A masters 2 (MSc. With 240 credits) in pharmacometrics / pharmaockinetics / pharmacodynamics / bioinformatics / microbiology or a related field is mandatory.
- Basic knowledge and practice of pharmacometric PKPD modelling and/or mathematical modelling of genetic and plasmidic transfer dynamics is mandatory.
- Basic knowledge and practice of basic microbiology experiments (Work in a BSL2 environment, MIC measurement of an antibiotic by microdilution, time-kill experiments) and flow cytometry is mandatory.
- Proficiency in written and oral English is a merit, B2 European level is a minimum.
- Familiarity with scientific programming languages (e.g. R, Python) is a merit

Application procedure:
- Send an email with a cover letter and a CV and one or two professional reference contact to This email address is being protected from spambots. You need JavaScript enabled to view it.This email address is being protected from spambots. You need JavaScript enabled to view it. and a cc to This email address is being protected from spambots. You need JavaScript enabled to view it.

 

 

 

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Anyone with an interest in PK/PD, dosing, resistance of anti-infectives, and outcome of antimicrobial therapy can apply to become a member of ISAP. We welcome applications from everywhere worldwide.

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